Revista da Sociedade Brasileira de Medicina Tropical (Apr 2013)

Susceptibility to amphotericin B of Candida spp. strains isolated in Ceará, Northeastern Brazil

  • Cecília Rocha da Silva,
  • Hemerson Iury Ferreira Magalhães,
  • Manoel Odorico de Moraes,
  • Hélio Vitoriano Nobre Júnior

DOI
https://doi.org/10.1590/0037-8682-1060-2013
Journal volume & issue
Vol. 46, no. 2
pp. 244 – 245

Abstract

Read online

Introduction Amphotericin B (AMB) is an antifungal agent used extensively in clinical medicine, yet resistance remains low. This study aims to evaluate the susceptibility of Candida spp. against AMB. Methods For broth microdilution susceptibility testing, 77 strains of Candida spp. were selected (32 C. albicans, 33 C. tropicalis, and 12 C. parapsilosis). The strains were considered susceptible when they exhibited MIC≤1.0µg/ml. Results None of the strains showed an MIC greater than 0.25µg/ml. Conclusions Further works are necessary, with a higher number of strains, to assess the validity of the results used in this study.

Keywords