Effects of hypothermia on skeletal ischemia
reperfusion injury in rats

Ekinci Şafak; Kaldırım Ümit; Akyıldız Faruk; Bilgiç Serkan; Koca Kenan; Poyrazoğlu Yavuz; Uysal Ozgür Selim; Turğut Hasan; Türkkan Selim; Erşen Ömer; Topal Turgut; Ozkan Huseyin

doi:10.1515/med-2015-0031

Open Medicine (Feb 2015)

Effects of hypothermia on skeletal ischemia reperfusion injury in rats

Ekinci Şafak,
Kaldırım Ümit,
Akyıldız Faruk,
Bilgiç Serkan,
Koca Kenan,
Poyrazoğlu Yavuz,
Uysal Ozgür Selim,
Turğut Hasan,
Türkkan Selim,
Erşen Ömer,
Topal Turgut,
Ozkan Huseyin

Affiliations

Ekinci Şafak: Department of Orthopaedics and Traumatology, Malatya Military Hospital, Malatya, Turkey
Kaldırım Ümit: Department of Emergency Medicine, Gulhane Military Medical Academy, Ankara, Turkey
Akyıldız Faruk: Department of Orthopaedics and Traumatology, Malatya Military Hospital, Malatya, Turkey
Bilgiç Serkan: Department of Orthopaedics and Traumatology, Haydarpaşa Military Hospital, İstanbul, Turkey
Koca Kenan: Department of Orthopaedics and Traumatology, Gulhane Military Medical Academy, Ankara, Turkey
Poyrazoğlu Yavuz: Department of General Surgery, Mevki Military Hospital, Ankara, Turkey
Uysal Ozgür Selim: Department of Emergency Medicine, Gulhane Military Medical Academy, Ankara, Turkey
Turğut Hasan: Department of Orthopaedics and Traumatology, Bursa Military Hospital, Bursa, Turkey
Türkkan Selim: Department of Orthopaedics and Traumatology, Gulhane Military Medical Academy, Ankara, Turkey
Erşen Ömer: Department of Orthopaedics and Traumatology, Erzurum Military Hospital, Erzurum, Turkey
Topal Turgut: Department of Physiology, Gulhane Military Medical Academy, Ankara, Turkey
Ozkan Huseyin: Department of Orthopaedics and Traumatology, Gulhane Military Medical Academy, Ankara, Turkey

DOI: https://doi.org/10.1515/med-2015-0031
Journal volume & issue: Vol. 10, no. 1

Abstract

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Objective: The aim of this study was to investigate the effect of hypothermia (H) on skeletal ischemia-reperfusion (IR) injury in rats by measuring malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), nitric oxide (NO), and interleukin-1 beta (IL-1β) in muscle, and measureing immunohistochemical- inducible nitric oxide synthase (iNOS) staining of skeletal muscle.

Published in Open Medicine

ISSN: 2391-5463 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Medicine
Website: https://www.degruyter.com/journal/key/med/html

About the journal

Abstract

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