Anais Brasileiros de Dermatologia (Feb 2016)

Cutaneous invasion from sarcomatoid urothelial carcinoma: clinical and dermatopathologic features

  • Fred Bernardes Filho,
  • Alessandro Severo Alves de Melo,
  • Andréa Rodriguez Cordovil Pires,
  • Omar Lupi,
  • Daniel Gama das Neves,
  • Margareth Fernandes da Cruz,
  • Bernard Kawa Kac

DOI
https://doi.org/10.1590/abd1806-4841.20164081
Journal volume & issue
Vol. 91, no. 1
pp. 73 – 79

Abstract

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Abstract In Brazil, without considering the non-melanoma skin tumors, bladder cancer in men is the eighth most common, and the urothelial carcinoma or transitional cell carcinoma is the most common among these. Cutaneous metastases from urothelial neoplasms appear as single or multiple erythematous, infiltrated nodules or plaques, and like other cases of distant disease, it is indicative of poor prognosis. The invasive urothelial carcinoma is recognized for its ability to present divergent differentiation and morphological variants. The sarcomatoid urothelial carcinoma is a rare cancer that consists of two different components: one composed of epithelial tissue and the other with sarcomatoid features of mesenchymal origin. The authors describe a case of cutaneous metastasis of sarcomatoid urothelial carcinoma in a 63-year-old male patient.

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