Haematologica (Dec 2007)

Successful unrelated cord blood transplantation for a patient with CD40 ligand deficiency

  • Yoichiro Tsuji,
  • Kohsuke Imai,
  • Yoichi Morinishi,
  • Kazuhiro Kogawa,
  • Masaaki Morino,
  • Shigeaki Nonoyama

DOI
https://doi.org/10.3324/haematol.11531
Journal volume & issue
Vol. 92, no. 12

Abstract

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We report a CD40 ligand deficiency (CD40LD) patient who was successfully treated with unrelated cord blood transplantation (URCBT). Conditioning regimen was busulfan and cyclophosphamide. The clinical course was uneventful and durable engraftment was achieved. This successful case encourages the use of URCB as an alternative donor source for CD40LD patients.