Tools for visualization and analysis of molecular networks, pathways, and -omics data

Abstract

Jose M Villaveces, Prasanna Koti, Bianca H Habermann Max Planck Institute of Biochemistry, Research Group Computational Biology, Martinsried, Germany Abstract: Biological pathways have become the standard way to represent the coordinated reactions and actions of a series of molecules in a cell. A series of interconnected pathways is referred to as a biological network, which denotes a more holistic view on the entanglement of cellular reactions. Biological pathways and networks are not only an appropriate approach to visualize molecular reactions. They have also become one leading method in -omics data analysis and visualization. Here, we review a set of pathway and network visualization and analysis methods and take a look at potential future developments in the field. Keywords: biological networks, reactions, proteins, genes, signaling, protein-protein interactions, organisms