Journal of Personalized Medicine (Dec 2023)

Hypothermia: Beyond the Narrative Review—The Point of View of Emergency Physicians and Medico-Legal Considerations

  • Gabriele Savioli,
  • Iride Francesca Ceresa,
  • Gaia Bavestrello Piccini,
  • Nicole Gri,
  • Alba Nardone,
  • Raffaele La Russa,
  • Angela Saviano,
  • Andrea Piccioni,
  • Giovanni Ricevuti,
  • Ciro Esposito

DOI
https://doi.org/10.3390/jpm13121690
Journal volume & issue
Vol. 13, no. 12
p. 1690

Abstract

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Hypothermia is a widespread condition all over the world, with a high risk of mortality in pre-hospital and in-hospital settings when it is not promptly and adequately treated. In this review, we aim to describe the main specificities of the diagnosis and treatment of hypothermia through consideration of the physiological changes that occur in hypothermic patients. Hypothermia can occur due to unfavorable environmental conditions as well as internal causes, such as pathological states that result in reduced heat production, increased heat loss or ineffectiveness of the thermal regulation system. The consequences of hypothermia affect several systems in the body—the cardiovascular system, the central and peripheral nervous systems, the respiratory system, the endocrine system and the gastrointestinal system—but also kidney function, electrolyte balance and coagulation. Once hypothermia is recognized, prompt treatment, focused on restoring body temperature and supporting vital functions, is fundamental in order to avert preventable death. It is important to also denote the fact that CPR has specificities related to the unique profile of hypothermic patients.

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