Memorias do Instituto Oswaldo Cruz (Aug 2016)

Comparative growth of spotted fever group Rickettsia spp. strains in Vero cells

  • Arannadia Barbosa Silva,
  • Myrian Morato Duarte,
  • Vinicius Figueiredo Vizzoni,
  • Ana Íris de Lima Duré,
  • Diego Montenegro Lopéz,
  • Rita de Maria Seabra Nogueira,
  • Carlos Augusto Gomes Soares,
  • Erik Machado-Ferreira,
  • Gilberto Salles Gazêta

DOI
https://doi.org/10.1590/0074-02760160093
Journal volume & issue
Vol. 111, no. 8
pp. 528 – 531

Abstract

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In Brazil, the spotted fever group (SFG) Rickettsia rickettsii and Rickettsia parkeri related species are the etiological agents of spotted fever rickettsiosis. However, the SFG, Rickettsia rhipicephali, that infects humans, has never been reported. The study of growth dynamics can be useful for understanding the infective and invasive capacity of these pathogens. Here, the growth rates of the Brazilian isolates R. rickettsii str. Taiaçu, R. parkeri str. At#24, and R. rhipicephali HJ#5, were evaluated in Vero cells by quantitative polymerase chain reaction. R. rhipicephali showed different kinetic growth compared to R. rickettsii and R. parkeri.

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