GPR87 promotes tumor cell invasion and mediates the immunogenomic landscape of lung adenocarcinoma

Rui Bai; Jianguo Zhang; Fajian He; Yangyi Li; Panpan Dai; Zhengrong Huang; Linzhi Han; Zhihao Wang; Yan Gong; Conghua Xie

doi:10.1038/s42003-022-03506-6

Communications Biology (Jul 2022)

GPR87 promotes tumor cell invasion and mediates the immunogenomic landscape of lung adenocarcinoma

Rui Bai,
Jianguo Zhang,
Fajian He,
Yangyi Li,
Panpan Dai,
Zhengrong Huang,
Linzhi Han,
Zhihao Wang,
Yan Gong,
Conghua Xie

Affiliations

Rui Bai: Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University
Jianguo Zhang: Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University
Fajian He: Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University
Yangyi Li: Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University
Panpan Dai: Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University
Zhengrong Huang: Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University
Linzhi Han: Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University
Zhihao Wang: Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University
Yan Gong: Department of Biological Repositories, Zhongnan Hospital of Wuhan University
Conghua Xie: Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University

DOI: https://doi.org/10.1038/s42003-022-03506-6
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 12

Abstract

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GPR87 is reported as a central player in lung adenocarcinoma and in resistance to immunotherapy, by promoting tumor cell invasion and mediating the immunogenomic landscape.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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