Química Nova (Dec 2005)

Tiossemicarbazonas: métodos de obtenção, aplicações sintéticas e importância biológica Thiosemicarbazones: preparation methods, synthetic applications and biological importance

  • Rômulo P. Tenório,
  • Alexandre J. S. Góes,
  • José G. de Lima,
  • Antônio R. de Faria,
  • Antônio J. Alves,
  • Thiago M. de Aquino

DOI
https://doi.org/10.1590/S0100-40422005000600018
Journal volume & issue
Vol. 28, no. 6
pp. 1030 – 1037

Abstract

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Thiosemicarbazones are a class of compounds known by their chemical and biological properties, such as antitumor, antibacterial, antiviral and antiprotozoal activity. Their ability to form chelates with metals has great importance in their biological activities. Their synthesis is very simple, versatile and clean, usually giving high yields. They are largely employed as intermediates, in the synthesis of others compounds. This article is a survey of some of these characteristics showing their great importance to organic and medicinal chemistry.

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