Research Progress on Cardiotoxicity of PD-1/PD-L1 Immune Checkpoint Inhibitors

Abstract

Cardiotoxicity is a serious complication of antineoplastic drugs. With the continuous development of antineoplastic drugs, immune checkpoint inhibitors have been used in the treatment of a variety of cancers. PD-1/PD-L1 immune checkpoint inhibitors have been widely concerned in recent years. This article reviews the manifestations and possible mechanisms of cardiotoxicity induced by PD-1/PD-L1 immune checkpoint inhibitors, and the detection methods and treatment of cardiotoxicity.

Keywords

• pd-1/pd-l1
• immune checkpoint inhibitors
• cardiotoxicity
• progress