Nintedanib for the treatment of symptomatic radiation pneumonitis. A Case Report

M.E. Kuipers; K.C.J. Van Doorn-Wink; P.E. Postmus

Heliyon (Jul 2024)

Nintedanib for the treatment of symptomatic radiation pneumonitis. A Case Report

M.E. Kuipers,
K.C.J. Van Doorn-Wink,
P.E. Postmus

Affiliations

M.E. Kuipers: Leiden University Medical Center (LUMC), Department of Pulmonology, C02-Q, Albinusdreef 2, 2333 ZA, Leiden, the Netherlands; Corresponding author.
K.C.J. Van Doorn-Wink: Leiden University Medical Center (LUMC), Department of Radiotherapy, K01-P, Albinusdreef 2, 2333 ZA, Leiden, the Netherlands
P.E. Postmus: Leiden University Medical Center (LUMC), Department of Pulmonology, C02-Q, Albinusdreef 2, 2333 ZA, Leiden, the Netherlands

Journal volume & issue: Vol. 10, no. 14
p. e34345

Abstract

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Radiation induced pneumonitis is a common side effect of thoracic radiotherapy. We report a case of a patient diagnosed with symptomatic radiation pneumonitis and a serious contra-indication for corticosteroids. For that reason, the patient was treated with nintedanib instead. After several weeks of treatment her symptoms and chest CT improved significantly. This case shows that nintedanib might be an effective treatment of radiation pneumonitis if corticosteroids are contra-indicated.

Published in Heliyon

ISSN: 2405-8440 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Science: Science (General); Social Sciences: Social sciences (General)
Website: https://www.cell.com/heliyon/home

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