Frontiers in Oncology (Apr 2024)

Case report: Highly response to low-dose brachytherapy in recurrent retroperitoneal leiomyosarcoma with FANCD2 frameshift mutation: a unique case study

  • Xiao li Liu,
  • Jinxin Zhao,
  • Xue min Di,
  • Guohui Cao,
  • Hongtao Zhang,
  • Juan Wang

DOI
https://doi.org/10.3389/fonc.2024.1339955
Journal volume & issue
Vol. 14

Abstract

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We report a case of recurrent retroperitoneal leiomyosarcoma in a male who achieved a rapid and robust but transient clinical response to low-dose iodine-125 brachytherapy. A FANCD2 frameshift mutation was detected by gene sequencing in the cancerous tissue.

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