Frontiers in Medicine (Oct 2020)

Locked-in Syndrome in a Young Patient Due to SARS-CoV-2: A Case Report

  • Saud Bin Abdul Sattar,
  • Qasim Zafar Iqbal,
  • Muhammad Adnan Haider,
  • Zeeshan Zia,
  • Muhammad Raphay Khan Niazi,
  • Muhammad Hanif,
  • Mukarram Jamat Ali,
  • Muhammad Aslam Khan

DOI
https://doi.org/10.3389/fmed.2020.574690
Journal volume & issue
Vol. 7

Abstract

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Coronavirus disease 2019 (COVID-19), apart from commonly involving the respiratory system, has its impact on the central nervous system, with a wide spectrum of clinical presentations ranging from headaches to ischemic strokes. The ongoing research regarding this novel disease has found that there is a very high prevalence of thrombotic episodes especially in critically ill patients when compared to severe presentation of other viral illnesses. This COVID-19-associated coagulopathy has a very complex etiology with the ability to form thrombus in arteries, veins, and microvasculatures of different organs. We present a unique case of a young woman with underlying COVID-19 who unfortunately developed locked-in syndrome due to bilateral pontine infarction during the course of her illness.

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