Mucinous adenocarcinoma in a neonate with congenital pulmonary malformation

Abstract

Congenital pulmonary airway malformation (CPAM) is a rare developmental abnormality of the lower respiratory tract, often diagnosed during routine prenatal ultrasonography.We report a full-term newborn female noted to have a large mass in the left hemithorax during prenatal ultrasound, at 35 weeks gestation. A multicystic lesion in the lower left chest was confirmed using a Chest Radiograph and Computed Tomography (CT) angiogram. Her hospital course was next followed by a left lower lobectomy, with resultant pathology of CPAM Type 1 and invasive mucinous adenocarcinoma. Though patients with asymptomatic CPAM are often managed by observation, our case of unexpected malignancy advocates early considerations towards Surgery.

Keywords

• Congenital pulmonary airway malformation (CPAM)
• Mucinous adenocarcinoma