Advanced characterization of microbeads replacement from cellulose acetate based on empty fruit bunches and dried jackfruit leaves

Abstract

The existing polymer microbeads for skin extraction ingredients have many disadvantages in environment. The application of cellulose has been proven in the pharmaceutical field in the form of beads on drug release can be a substitute alternative to polymer microbeads that will be prohibited. Based on several criteria and past researches, cellulose acetate meets the criteria for microbeads replacement. Cellulose is available in large quantities in the world, and many studies has proven its application on a wide scope. Empty Fruit Bunches (EFB) and Dried Jackfruit Leaves (DJL) are widely distributed raw materials in Indonesia so that they can be used as a substitute for microbeads. The FTIR and SEM-EDX tests were conducted to determine the functional groups of cellulose acetate and morphology formation of cellulose acetate both raw materials and their chemical composition. In FTIR testing, the typical absorption of EFB and DJL cellulose acetate is produced by C=O groups for EFB at wavelength 1721,36 cm-1 and DJL at wavelength 1725,22 cm-1, whereas at SEM-EDX, DJL cellulose acetate asymmetrical cylinders and rare small pores on the surface and cellulose acetate TKKS cylindrical symmetrical with small pores on its surface. The chemical components of EFB and DJL cellulose acetate exhibit organic elements of carbon (C) and oxygen (O).