Nature Communications (Jan 2019)
Strigolactone perception and deactivation by a hydrolase receptor DWARF14
- Yoshiya Seto,
- Rei Yasui,
- Hiromu Kameoka,
- Muluneh Tamiru,
- Mengmeng Cao,
- Ryohei Terauchi,
- Akane Sakurada,
- Rena Hirano,
- Takaya Kisugi,
- Atsushi Hanada,
- Mikihisa Umehara,
- Eunjoo Seo,
- Kohki Akiyama,
- Jason Burke,
- Noriko Takeda-Kamiya,
- Weiqiang Li,
- Yoshinori Hirano,
- Toshio Hakoshima,
- Kiyoshi Mashiguchi,
- Joseph P. Noel,
- Junko Kyozuka,
- Shinjiro Yamaguchi
Affiliations
- Yoshiya Seto
- Department of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University
- Rei Yasui
- Department of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University
- Hiromu Kameoka
- Graduate School of Agricultural and Life Science, University of Tokyo, Yayoi, Bunkyo
- Muluneh Tamiru
- Iwate Biotechnology Research Center
- Mengmeng Cao
- Department of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University
- Ryohei Terauchi
- Iwate Biotechnology Research Center
- Akane Sakurada
- Department of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University
- Rena Hirano
- Department of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University
- Takaya Kisugi
- Department of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University
- Atsushi Hanada
- Department of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University
- Mikihisa Umehara
- RIKEN Plant Science Center, Tsurumi
- Eunjoo Seo
- RIKEN Plant Science Center, Tsurumi
- Kohki Akiyama
- Graduates School of Life and Environmental Sciences, Osaka Prefecture University
- Jason Burke
- Jack H. Skirball Center for Chemical Biology and Proteomics, Salk Institute for Biological Studies
- Noriko Takeda-Kamiya
- RIKEN Plant Science Center, Tsurumi
- Weiqiang Li
- RIKEN Plant Science Center, Tsurumi
- Yoshinori Hirano
- Structural Biology Laboratory, Nara Institute of Science and Technology
- Toshio Hakoshima
- Structural Biology Laboratory, Nara Institute of Science and Technology
- Kiyoshi Mashiguchi
- Department of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University
- Joseph P. Noel
- Jack H. Skirball Center for Chemical Biology and Proteomics, Salk Institute for Biological Studies
- Junko Kyozuka
- Department of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University
- Shinjiro Yamaguchi
- Department of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University
- DOI
- https://doi.org/10.1038/s41467-018-08124-7
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 10
Abstract
Cleavage of strigolactone by the D14 receptor was assumed to produce an active intermediate that promotes signaling. Here the authors show that D14 activity is not dependent on cleavage activity and propose a new model whereby ligand hydrolysis serves to deactivate strigolactone signaling.
