Jornal Brasileiro de Pneumologia (Feb 2015)

Endobronchial ultrasound-guided transbronchial needle aspiration for lung cancer staging: early experience in Brazil,

  • Viviane Rossi Figueiredo,
  • Paulo Francisco Guerreiro Cardoso,
  • Márcia Jacomelli,
  • Sérgio Eduardo Demarzo,
  • Addy Lidvina Mejia Palomino,
  • Ascédio José Rodrigues,
  • Ricardo Mingarini Terra,
  • Paulo Manoel Pego-Fernandes,
  • Carlos Roberto Ribeiro Carvalho

DOI
https://doi.org/10.1590/S1806-37132015000100004
Journal volume & issue
Vol. 41, no. 1
pp. 23 – 30

Abstract

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Objective: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive, safe and accurate method for collecting samples from mediastinal and hilar lymph nodes. This study focused on the initial results obtained with EBUS-TBNA for lung cancer and lymph node staging at three teaching hospitals in Brazil. Methods: This was a retrospective analysis of patients diagnosed with lung cancer and submitted to EBUS-TBNA for mediastinal lymph node staging. The EBUS-TBNA procedures, which involved the use of an EBUS scope, an ultrasound processor, and a compatible, disposable 22 G needle, were performed while the patients were under general anesthesia. Results: Between January of 2011 and January of 2014, 149 patients underwent EBUS-TBNA for lymph node staging. The mean age was 66 ± 12 years, and 58% were male. A total of 407 lymph nodes were sampled by EBUS-TBNA. The most common types of lung neoplasm were adenocarcinoma (in 67%) and squamous cell carcinoma (in 24%). For lung cancer staging, EBUS-TBNA was found to have a sensitivity of 96%, a specificity of 100%, and a negative predictive value of 85%. Conclusions: We found EBUS-TBNA to be a safe and accurate method for lymph node staging in lung cancer patients.

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