Journal of Pharmacy and Bioallied Sciences (Apr 2024)

Unveiling the In Vitro Anti-Biofilm Potential of Lactobacillus rhamnosus Against Saliva-Based Pathogens: A Gender-Age-Area Specific Study

  • Adhikary Tamanna,
  • Mishra Pallavi,
  • Kumar Harish,
  • Bhuyan Lipsa,
  • Behera Subhransu S,
  • Nivedita Suchismita

DOI
https://doi.org/10.4103/jpbs.jpbs_1185_23
Journal volume & issue
Vol. 16, no. 6
pp. 1764 – 1770

Abstract

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Probiotics, like lactobacilli and bifidobacteria, benefit health by populating the digestive system, which houses numerous microbial species. Studies demonstrate their ability to inhibit biofilm formation, crucial in preventing oral conditions like dental caries. Our research evaluated a probiotic strain’s anti-biofilm efficacy against oral pathogens in 45 individuals’ saliva, alongside its biofilm-forming potential. Analysis revealed significant biofilm inhibition in 36 samples. Comparisons based on age, gender, and geography further supported these findings. We propose further exploration of probiotics tailored to specific demographics to enhance oral health outcomes, suggesting a promising avenue for preventing oral microbial diseases.

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