Molecules (Nov 2022)

Recent Research and Application Prospect of Functional Oligosaccharides on Intestinal Disease Treatment

  • Tong Xu,
  • Ruijie Sun,
  • Yuchen Zhang,
  • Chen Zhang,
  • Yujing Wang,
  • Zhuo A. Wang,
  • Yuguang Du

DOI
https://doi.org/10.3390/molecules27217622
Journal volume & issue
Vol. 27, no. 21
p. 7622

Abstract

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The intestinal tract is an essential digestive organ of the human body, and damage to the intestinal barrier will lead to various diseases. Functional oligosaccharides are carbohydrates with a low degree of polymerization and exhibit beneficial effects on human intestinal health. Laboratory experiments and clinical studies indicate that functional oligosaccharides repair the damaged intestinal tract and maintain intestinal homeostasis by regulating intestinal barrier function, immune response, and intestinal microbial composition. Functional oligosaccharides treat intestinal disease such as inflammatory bowel disease (IBD) and colorectal cancer (CRC) and have excellent prospects for therapeutic application. Here, we present an overview of the recent research into the effects of functional oligosaccharides on intestinal health.

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