A Universal Field-of-View Mask Segmentation Method on Retinal Images From Fundus Cameras

Abstract

One of the first steps in the retinal image preprocessing is cropping the Field of View (FOV) area and scaling it into a template of a predefined size. Fundus cameras of different producers record digital images of the retina of various sizes, and the FOV area containing helpful information can be from 43 to 98% of the image area. For automated analysis of retinal images and detection of DR, it is necessary to segment the FOV region and cut it out from the image. This is important to preserve microaneurysms and small capillaries in the retinal image as much as possible, since neural network methods always reduce the original images to a predefined size. In this paper, we propose a universal method for FOV segmentation based on the ideas of histograms and thresholds. We compared 11 methods for segmenting FOV regions on the four most commonly used retinal image grayscale representations. In total, we compared 35 variants of segmentation and evaluated the obtained results by four functions: Jaccard index, Matthews correlation coefficient (MCC), accuracy and balanced accuracy. All options were tested on 7000 images from nine of the largest databases. The images were generated by 100 different fundus cameras. The following observations have been extracted through extensive comparative experiments namely: 1) segmentation of the FOV area should be performed on the grayscale image obtained from the red channel; 2) for more accurate segmentation, a logarithmic transformation should be applied to the grayscale image; 3) the FOV area mask can be segmented by a global threshold calculated by Otsu’s method; 4) global thresholding based on analysis of histogram peaks does not provide advantages over binarization by Otsu’s method applied to the logarithmic transformation of the image.

Keywords

• Fundus image
• field of view (FOV) mask
• FOV segmentation
• dataset
• image representation