Applied Surface Science Advances (Jun 2022)
Research on design of micron bubble dressing
Abstract
Dogs that suffer from local dermatitis are not easily treated by medicine bath. To achieve the effect of bath treatment, a prototype of a dressing embedded with micron bubbles containing an antibacterial agent was designed in this study to treat the disease. In the experiment, a generator of micron bubbles, an aqueous antibacterial agent, and a nozzle comprising high-density stainless steel screens were used to generate micron bubbles containing the antibacterial agent, which were embedded in the dressing so that the bubbles could come into contact with S. pseudintermedius. Meanwhile, the flow of the micron bubbles and bactericidal action time were adjusted to identify the effective combinations of conditions. Specifically, a high-density stainless steel screen of one, two, or three layers; two different dressings; two flows of micron bubbles; and three bactericidal action times were tested in the design process. The three different layers of the screen could generate micron bubbles of the three different sizes used in the disinfection experiment. Then, statistical analysis of percentages of survived colonies was performed against the various combinations. The results showed that (1) the micron bubbles containing antibacterial agent generated by a high-density stainless steel screen nozzle and embedded in a dressing can effectively disinfect S. pseudintermedius; (2) the smaller the size of the micron bubbles, the better the disinfection effectiveness; (3) the variables of the flow of micron bubbles, bactericidal action time, and layers of the high-density stainless steel screen are the main factors affecting the disinfection of S. pseudintermedius. The overall disinfection effectiveness was 84.68%, with some combinations being 100% effective. The disinfecting solution for S. pseudintermedius with the micron bubble dressing proposed in this study aims to minimize canine local dermatitis and reduce medical consultation frequency.
