The Magnaporthe oryzae effector Avr-PikD suppresses rice immunity by inhibiting an LSD1-like transcriptional activator

Jiayuan Guo; Yiling Wu; Jianqiang Huang; Kaihui Yu; Meilian Chen; Yijuan Han; Zhenhui Zhong; Guodong Lu; Yonghe Hong; Zonghua Wang; Xiaofeng Chen

Crop Journal (Apr 2024)

The Magnaporthe oryzae effector Avr-PikD suppresses rice immunity by inhibiting an LSD1-like transcriptional activator

Jiayuan Guo,
Yiling Wu,
Jianqiang Huang,
Kaihui Yu,
Meilian Chen,
Yijuan Han,
Zhenhui Zhong,
Guodong Lu,
Yonghe Hong,
Zonghua Wang,
Xiaofeng Chen

Affiliations

Jiayuan Guo: Fujian Universities Engineering Research Center of Marine Biology and Drugs, Fuzhou Institute of Oceanography, College of Geography and Oceanography, Minjiang University, Fuzhou 350108, Fujian, China; Ministerial and Provincial Joint Innovation Center for Safety Production of Cross-Strait Crops, Minjiang University, Fuzhou 350108, Fujian, China; State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou 350002, Fujian, China
Yiling Wu: State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou 350002, Fujian, China
Jianqiang Huang: State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou 350002, Fujian, China
Kaihui Yu: Ministerial and Provincial Joint Innovation Center for Safety Production of Cross-Strait Crops, Minjiang University, Fuzhou 350108, Fujian, China; State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou 350002, Fujian, China
Meilian Chen: Fujian Universities Engineering Research Center of Marine Biology and Drugs, Fuzhou Institute of Oceanography, College of Geography and Oceanography, Minjiang University, Fuzhou 350108, Fujian, China; Ministerial and Provincial Joint Innovation Center for Safety Production of Cross-Strait Crops, Minjiang University, Fuzhou 350108, Fujian, China
Yijuan Han: Fujian Universities Engineering Research Center of Marine Biology and Drugs, Fuzhou Institute of Oceanography, College of Geography and Oceanography, Minjiang University, Fuzhou 350108, Fujian, China; Ministerial and Provincial Joint Innovation Center for Safety Production of Cross-Strait Crops, Minjiang University, Fuzhou 350108, Fujian, China
Zhenhui Zhong: State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou 350002, Fujian, China
Guodong Lu: State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou 350002, Fujian, China
Yonghe Hong: Rice Research Institute, Fujian Academy of Agricultural Sciences, Fuzhou 350018, Fujian, China; State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou 350002, Fujian, China; Corresponding authors.
Zonghua Wang: Fujian Universities Engineering Research Center of Marine Biology and Drugs, Fuzhou Institute of Oceanography, College of Geography and Oceanography, Minjiang University, Fuzhou 350108, Fujian, China; Ministerial and Provincial Joint Innovation Center for Safety Production of Cross-Strait Crops, Minjiang University, Fuzhou 350108, Fujian, China; State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou 350002, Fujian, China; Corresponding authors.
Xiaofeng Chen: Fujian Universities Engineering Research Center of Marine Biology and Drugs, Fuzhou Institute of Oceanography, College of Geography and Oceanography, Minjiang University, Fuzhou 350108, Fujian, China; Ministerial and Provincial Joint Innovation Center for Safety Production of Cross-Strait Crops, Minjiang University, Fuzhou 350108, Fujian, China; Corresponding authors.

Journal volume & issue: Vol. 12, no. 2
pp. 482 – 492

Abstract

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Avirulence effectors (Avrs), encoded by plant pathogens, can be recognized by plants harboring the corresponding resistance proteins, thereby initiating effector-triggered immunity (ETI). In susceptible plants, however, Avrs can function as effectors, facilitating infection via effector-triggered susceptibility (ETS). Mechanisms of Avr-mediated ETS remain largely unexplored. Here we report that the Magnaporthe oryzae effector Avr-PikD enters rice cells via the canonical cytoplasmic secretion pathway and suppresses rice basal defense. Avr-PikD interacts with an LSD1-like transcriptional activator AKIP30 of rice, and AKIP30 is also a positive regulator of rice immunity, whereas Avr-PikD impedes its nuclear localization and suppresses its transcriptional activity. In summary, M. oryzae delivers Avr-PikD into rice cells to facilitate ETS by inhibiting AKIP30-mediated transcriptional regulation of immune response against M. oryzae.

Published in Crop Journal

ISSN: 2095-5421 (Print); 2214-5141 (Online)
Publisher: KeAi Communications Co., Ltd.
Country of publisher: China
LCC subjects: Agriculture: Agriculture (General)
Website: https://www.keaipublishing.com/en/journals/the-crop-journal/

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