A cross-comparative pharmacokinetic study of Klimalanin (ingestion or sublingual intake)

Abstract

Beta-alanine (Klimalanin) is generally used for the treatment and prevention of vasomotor disturbances (hot flushes) in menopausal period. This paper presents the results of a comparative analysis of the beta-alanine pharmacokinetics with a single ingestion and sublingual intake in the group of 12 volunteers. The comparison showed that sublingual administration was characterized by a faster and more intense pharmacokinetics, and higher concentrations of active beta-alanine in the blood plasma.

Keywords

• beta-alanine
• hot flushes
• menopause
• klimalanin