Nature Communications (Dec 2016)

Tectal-derived interneurons contribute to phasic and tonic inhibition in the visual thalamus

  • Polona Jager,
  • Zhiwen Ye,
  • Xiao Yu,
  • Laskaro Zagoraiou,
  • Hong-Ting Prekop,
  • Juha Partanen,
  • Thomas M. Jessell,
  • William Wisden,
  • Stephen G. Brickley,
  • Alessio Delogu

DOI
https://doi.org/10.1038/ncomms13579
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 14

Abstract

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The development and function of thalamic interneurons is only partially understood. Here the authors describe the unexpected mesencephalic origin of the GABAergic interneurons of the visual thalamus that provide both phasic and tonic modulation of thalamic relay neuron excitability.