Thrombosis Update (Jan 2021)

Magnetic resonance thrombus imaging for the differentiation of chronic versus (sub)acute cerebral vein thrombosis: A case report

  • Lisette F. van Dam,
  • Anne van der Meij,
  • Lucia J.M. Kroft,
  • Guido R. van Haren,
  • Menno V. Huisman,
  • Marieke J.H. Wermer,
  • Nyika D. Kruyt,
  • Marianne A.A. van Walderveen,
  • Frederikus A. Klok

Journal volume & issue
Vol. 2
p. 100039

Abstract

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The diagnosis of cerebral vein thrombosis (CVT) can be difficult. Patients with suspected CVT, in whom venous sinuses are affected by intracranial tumours or after intracranial surgery constitutes a particular challenging setting. Magnetic resonance non-contrast thrombus imaging (MR-NCTI) is a new magnetic resonance imaging (MRI) technique that has previously been shown to be accurate in the diagnosis of a first CVT and difficult-to-diagnose venous thrombosis in other anatomical locations. In this case report, a patient with a medical history of craniotomy for parieto-occipital meningioma was suspected of an acute CVT, but had an inconclusive computed tomography (CT) and MRI venography. MR-NCTI showed no abnormalities diagnostic for (sub)acute CVT and thus cerebral sinus occlusion was most likely a chronic thrombus or a result of residual meningioma tissue. Anticoagulant treatment was discontinued and she was discharged from hospital in good health. This case shows that MR-NCTI may be a valuable additional imaging test in complex cases in whom CT and MRI venography could not exclude acute CVT.

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