Nature Communications (Sep 2021)

Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding

  • Fangjun Yu,
  • Zhigang Wang,
  • Tianpeng Zhang,
  • Xun Chen,
  • Haiman Xu,
  • Fei Wang,
  • Lianxia Guo,
  • Min Chen,
  • Kaisheng Liu,
  • Baojian Wu

DOI
https://doi.org/10.1038/s41467-021-25674-5
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 15

Abstract

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Tissue circadian clocks contribute to the regulation of physiology and metabolism. Here the authors investigate the role of the intestinal circadian clock in energy homeostasis and show that the intestinal clock acts as an accelerator in dietary fat absorption.