Journal of Contemporary Medicine (Jan 2021)
Effects Of Age, Body Mass Index, Complete Blood Count Parameters, and Biochemical Parameters on Stable COPD Patients
Abstract
Aim: Chronic obstructive pulmonary disease (COPD) is worldwide and mainly affects the elderly. It is often impossible to define COPD with specific lines, and it has no complete cure procedure, mostly established by guidelines. The GOLD guideline uses a sectional COPD evaluation approach to group patients by symptoms and former history of exacerbations. The concurrent detection of various biomarkers reflecting different pathobiological pathways might help recognize patients with an increased risk of death. Studies showed that obesity is related to decreased lung function in the general population due to respiratory mechanics, muscular discomfort, and breath control.Material and Method: Ninety patients with COPD, whose mean age was 62, and 74% were male, were divided into four groups as A, B, C, and D according to the GOLD classification, were included in our study. Analyses were conducted to investigate the association between biochemical parameters, BMI, age, gender, and disease severity, according to GOLD subgroups.Results: It has been demonstrated that COPD patients are generally over the age of 40 and age correlates with the severity of the disease consistent with previous studies. Our study has shown that COPD usually occurs over the age of 40, and there is a relationship between advanced age and the severity of COPD.Conclusion: Our results are consistent with previous studies where COPD patients are usually over 40 years old, and age is linked to disease severity. While the BMI values of the patients in group B were higher than those of group A, it was compatible with studies showing the relationship between obesity and severity of COPD; being higher than C and D groups was consistent with the studies revealing the obesity paradox. Crp, Procalcitonin, Sedimentation, Calcium, Magnesium levels, and other complete blood count values showed no significant difference between GOLD groups.
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