The kinetics study on 5- formyltetrahydrofolic acid degradation and 5,10- methenyltetrahydrofolic acid formation during thermal and combined high pressure thermal treatments

Abstract

The effect of different pHs (3.4 to 7.0) on 5-formyltetrahydrofolic acid (5-CHOH4PteGlu) stability during thermal (80-110°C) and high pressure thermal (100-800 MPa/65-70°C) processing was studied. The results showed that (i) the degradation of 5-CHOH4PteGlu during treatments (in the presence of ascorbic acid) was not only due to oxidation but also due to a conversion to 5,10-methenyltetrahydrofolic acid (5,10-CH=H4PteGlu), (ii) multiple response analysis was successfully applied to describe the kinetics of 5-CHOH4PteGlu degradation during thermal and/or high pressure processing.

Keywords

• Kinetic
• pressure
• temperature
• 5-CHOH4PteGlu
• 5
• 10-CH=H4PteGlu