PLoS ONE (Jan 2023)

Breaking the 30-day barrier: Long-term effectiveness of a nurse-led 7-step transitional intervention program in heart failure.

  • Lidia Alcoberro,
  • Pedro Moliner,
  • Joan Vime,
  • Santiago Jiménez-Marrero,
  • Alberto Garay,
  • Sergi Yun,
  • Alexandra Pons-Riverola,
  • Raúl Ramos-Polo,
  • Mar Ras-Jiménez,
  • Marta Tajes,
  • Encarna Hidalgo,
  • Esther Calero,
  • Marta Ruiz,
  • Nuria José-Bazán,
  • Carles Ferre,
  • Cristina Delso,
  • Laia Alcober,
  • Cristina Enjuanes,
  • Josep Comin-Colet

DOI
https://doi.org/10.1371/journal.pone.0279815
Journal volume & issue
Vol. 18, no. 2
p. e0279815

Abstract

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Background and aimsHeart failure (HF) programs successfully reduce 30-day readmissions. However, conflicting data exist about its sustained effects afterwards and its impact on mortality. We evaluated whether the impact of a new nurse-led coordinated transitional HF program extends to longer periods of time, including 90 and 180 days after discharge.Methods and resultsWe designed a natural experiment to undertake a pragmatical evaluation of the implementation of the program. We compared outcomes between patients discharged with HF as primary diagnosis in Period #1 (pre-program; Jan 2017-Aug 2017) and those discharged during Period #2 (HF program; Sept 2017-Jan 2019). Primary endpoint was the composite of all-cause death or all-cause hospitalization 90 and 180 days after discharge. 440 patients were enrolled: 123 in Period #1 and 317 in Period #2. Mean age was 75±9 years. There were more females in Period #2 (p = 0.025), with no other significant differences between periods. The primary endpoint was significantly reduced in the HF program group, at 90 [adjusted OR 0.31 (0.18-0.53), p ConclusionA new nurse-led coordinated transitional bundle of interventions model reduces the composite endpoint of all-cause death and all-cause hospitalization both at 90 and 180 days after a discharge for HF, also in high-risk populations. Such a decrease is driven by a reduction of CV and HF hospitalization. Reduction of all-cause mortality was also observed when the full model including a more exhaustive discharge planning process was implemented.