Arquivos de Neuro-Psiquiatria ()

No correlation was observed between vitamin D levels and disability of patients with multiple sclerosis between latitudes 18° and 30° South

  • Yara Dadalti Fragoso,
  • Tarso Adoni,
  • Soniza Vieira Alves-Leon,
  • Samira L. Apostolos-Pereira,
  • Walter Oleschko Arruda,
  • Joseph B. Bidin Brooks,
  • Henrique S. Rodrigues Cal,
  • Carlos A. Albuquerque Damasceno,
  • Paulo Diniz Gama,
  • Marcus V. Magno Goncalves,
  • Carlos A. da Silva de Jesus,
  • Suzana C. Nunes Machado,
  • Letícia Fezer Mansur,
  • Andre P. da Cunha Matta,
  • Maria Fernanda Mendes,
  • Rogerio Rizo Morales,
  • Adaucto Wanderley da Nobrega-Jr,
  • Monica K. Fiuza Parolin,
  • Mario Pietro Peres,
  • Marlise de Castro Ribeiro,
  • Heloisa Helena Ruocco,
  • Simone Scherpenhuijzen,
  • Fabio Siquinelli,
  • Patrick N. Stoney,
  • Daniel Lima Varela,
  • Audred Cristina Biondo Eboni,
  • Caroline Vieira Spessotto,
  • Elisa Teixeira da Rocha,
  • Pamela Emanuele Lacerda

DOI
https://doi.org/10.1590/0004-282x20160173
Journal volume & issue
Vol. 75, no. 1
pp. 3 – 8

Abstract

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ABSTRACT Objective: Vitamin D has taken center stage in research and treatment of multiple sclerosis (MS). The objective of the present study was to assess the serum vitamin D levels of a large population of patients with MS and controls living in a restricted tropical area. Methods: Data from 535 patients with MS and 350 control subjects were obtained from 14 cities around the Tropic of Capricorn. Results: The mean serum 25-OH vitamin D level was 26.07 ± 10.27 ng/mL for the control subjects, and 28.03 ± 12.19 ng/mL for patients with MS. No correlation was observed between vitamin D levels and the disability of patients over the disease duration. Conclusion: At least for the region around the Tropic of Capricorn, serum levels of vitamin D typically are within the range of 20 to 30 ng/mL for controls and patients with MS.

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