Bone Mineral Density Assessment in Ankylosing Spondylitis and Characteristics of Bone Turnover Parameters

Abstract

Ankylosing spondylitis, characterised with excessive new bone formation and calcification in spine and peripheral joints, causes osteoporosis which is a general component of inflammatory arthritis. Since is excessive bone formation affects bone mineral density, there are problems in diagnosis and follow-up of osteoporosis efforts made for finding the right diagnostic tool. Besides bone metabolism and turn-over in inflammatory diseases should be known in detail, because it has a place in diagnosis and follow-up. In this review, bone mineral density in ankylosing spondylitis, the importance and usage of bone turn-over parameters are discussed in the light of literature data.

Keywords

• Ankylosing spondylitis
• osteoporosis
• bone mineral density
• bone formation and resorbtion markers