Nature Communications (Nov 2022)

Modular stimuli-responsive hydrogel sealants for early gastrointestinal leak detection and containment

  • Alexandre H. C. Anthis,
  • Maria Paulene Abundo,
  • Anna L. Neuer,
  • Elena Tsolaki,
  • Jachym Rosendorf,
  • Thomas Rduch,
  • Fabian H. L. Starsich,
  • Bernhard Weisse,
  • Vaclav Liska,
  • Andrea A. Schlegel,
  • Mikhail G. Shapiro,
  • Inge K. Herrmann

DOI
https://doi.org/10.1038/s41467-022-34272-y
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 15

Abstract

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Digestive surgical leaks manifesting days after a successful surgery can lead to severe complications and affect healthcare worldwide. Here, the authors address the problem holistically with a hydrogel patch capable of sealing tissues, while detecting imminent leaks via a smartphone-operated ultrasound probe.