Identification of a Covalent Importin‑5 Inhibitor, Goyazensolide, from a Collective Synthesis of Furanoheliangolides

• Weilong Liu,
• Rémi Patouret,
• Sofia Barluenga,
• Michael Plank,
• Robbie Loewith,
• Nicolas Winssinger

Affiliations

Weilong Liu

Department of Organic Chemistry, NCCR Chemical Biology, Faculty of Science, University of Geneva, Geneva, Switzerland

Rémi Patouret

Department of Organic Chemistry, NCCR Chemical Biology, Faculty of Science, University of Geneva, Geneva, Switzerland

Sofia Barluenga

Department of Organic Chemistry, NCCR Chemical Biology, Faculty of Science, University of Geneva, Geneva, Switzerland

Michael Plank

Department of Molecular Biology, NCCR Chemical Biology, Faculty of Science, University of Geneva, Geneva, Switzerland

Robbie Loewith

Department of Molecular Biology, NCCR Chemical Biology, Faculty of Science, University of Geneva, Geneva, Switzerland

Nicolas Winssinger

Department of Organic Chemistry, NCCR Chemical Biology, Faculty of Science, University of Geneva, Geneva, Switzerland