Nature Communications (Mar 2018)

The global distribution and spread of the mobilized colistin resistance gene mcr-1

  • Ruobing Wang,
  • Lucy van Dorp,
  • Liam P. Shaw,
  • Phelim Bradley,
  • Qi Wang,
  • Xiaojuan Wang,
  • Longyang Jin,
  • Qing Zhang,
  • Yuqing Liu,
  • Adrien Rieux,
  • Thamarai Dorai-Schneiders,
  • Lucy Anne Weinert,
  • Zamin Iqbal,
  • Xavier Didelot,
  • Hui Wang,
  • Francois Balloux

DOI
https://doi.org/10.1038/s41467-018-03205-z
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 9

Abstract

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The recent plasmid-mediated spread of the mobilized colistin resistance gene mcr-1 poses a significant public health threat, requiring worldwide monitoring and surveillance. Here, Wang et al. compile and analyze a data set of 457 mcr-1-positive sequenced isolates to investigate the origin and global distribution of mcr-1.