Reserarch on the Formulation Process of Malt Chewable Tablets and Its Digestion Promoting Function

Abstract

Study on the formulation process of malt chewable tablets and its digestion promoting function.Using a method combining orthogonal experiment and fuzzy comprehensive evaluation to study the formulation process of malt chewable tablets; using small intestine ink advance rate of mice， pepsin excretion of rats， and animal weight change as indicators to study the digestion promoting function of malt chewable tablets. The best formulas are as follows: citric acid is 2%， stevioside is 1%， microcrystalline cellulose is 40%， and magnesium stearate is 1%. 2.67 g/kg BW (body weight) of malt chewable tablets can improve the ink advancing rate of the small bowel movement experiment in mice (P＜0.001)， and the chewable tablets had no adverse effects on rat weight gain， food intake， and food utilization. Malt chewable tablets preparation process is stable and reliable， and the animal function experiments show that it has the function of promoting digestion.

Keywords

• malt chewable tablets
• formulat
• preparation process
• digestive function
• animal experiment