Generation of an induced pluripotent stem cell line SDPHi002-A from a patient with lung cancer

Dan Ai; Xiaomeng Yang; Xinyu Li; Ning Liu; Xuexue Xie; Yi Liu; Wei Song

Stem Cell Research (Jun 2023)

Generation of an induced pluripotent stem cell line SDPHi002-A from a patient with lung cancer

Dan Ai,
Xiaomeng Yang,
Xinyu Li,
Ning Liu,
Xuexue Xie,
Yi Liu,
Wei Song

Affiliations

Dan Ai: Department of Oncology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China
Xiaomeng Yang: Pediatric Research Institute, Children’s Hospital Affiliated to Shandong University, Jinan 250022, China
Xinyu Li: Department of Oncology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China
Ning Liu: Pediatric Research Institute, Children’s Hospital Affiliated to Shandong University, Jinan 250022, China
Xuexue Xie: Shandong University of Traditional Chinese Medicine, Class of 2020, Doctoral Candidates, Jinan 250355, China
Yi Liu: Pediatric Research Institute, Children’s Hospital Affiliated to Shandong University, Jinan 250022, China; Corresponding authors.
Wei Song: Department of Oncology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China; Corresponding authors.

Journal volume & issue: Vol. 69
p. 103096

Abstract

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Here, an induced pluripotent stem cell (iPSC) line from a patient with lung neuroendocrine carcinoma was generated. The iPSCs were developed using nonintegrating episomal vectors carrying OCT4, SOX2, KLF4, BCL-XL and c-MYC. The established iPSCs (SDPHi002-A) had normal karyotype, excellent differentiation potential in vitro, showing pluripotent stem cell morphology and high expression of pluripotent markers.

Published in Stem Cell Research

ISSN: 1873-5061 (Print); 1876-7753 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Biology (General)
Website: https://www.journals.elsevier.com/stem-cell-research

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