Nature Communications (May 2021)

Transcranial alternating current stimulation entrains alpha oscillations by preferential phase synchronization of fast-spiking cortical neurons to stimulation waveform

  • Wei A. Huang,
  • Iain M. Stitt,
  • Ehsan Negahbani,
  • D. J. Passey,
  • Sangtae Ahn,
  • Marshall Davey,
  • Moritz Dannhauer,
  • Thien T. Doan,
  • Anna C. Hoover,
  • Angel V. Peterchev,
  • Susanne Radtke-Schuller,
  • Flavio Fröhlich

DOI
https://doi.org/10.1038/s41467-021-23021-2
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 20

Abstract

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Transcranial alternating current stimulation (tACS) can modulate cortical oscillations and associated long-lasting cognitive and behavioral functions in humans. Here, the authors provide in vivo evidence in ferrets on the mechanism of how weak electric fields in tACS can entrain neuronal activity.