Communications Biology (Mar 2023)
CD115− monocytic myeloid-derived suppressor cells are precursors of OLFM4high polymorphonuclear myeloid-derived suppressor cells
Abstract
CD115− monocytic MDSCs, functionally distinct from CD115+ monocytic MDSCs, increase in the blood and bone marrow as tumor progresses and can give rise to OLFM4hi polymorphonuclear MDSCs outside the tumor mass.