PLoS ONE (Jan 2021)

Impact of extent of internal acoustic meatus tumor removal using translabyrinthine approach for acoustic neuroma surgery.

  • Kuan-Wei Chiang,
  • Sanford P C Hsu,
  • Tsui-Fen Yang,
  • Mao-Che Wang

DOI
https://doi.org/10.1371/journal.pone.0253338
Journal volume & issue
Vol. 16, no. 8
p. e0253338

Abstract

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ObjectivesMany studies have investigated the surgical outcome and predictive factors of acoustic neuroma using different approaches. The present study focused on large tumors due to the greater likelihood of internal acoustic meatus involvement and the greater application of surgical intervention than radiosurgery. There have been no previous reports on outcomes of internal acoustic meatus tumor removal. We investigated the impact of the extent of internal acoustic meatus tumor removal using a translabyrinthine approach for large acoustic neuroma surgery and predictive factors of tumor control.MethodsThis retrospective study reviewed 104 patients with large cerebellopontine angle tumor >3 cm treated by translabyrinthine approach microsurgery. Predictive factors of postoperative facial palsy, tumor control, and extent of internal acoustic meatus tumor removal were assessed.ResultsThe mean tumor size was 38.95 ± 6.83 mm. Postoperative facial function showed 76.9% acceptable function (House-Brackmann grade 1 or 2) six months after surgery. The extent of internal acoustic meatus tumor removal was a statistically significant predictor factor of poor postoperative facial function. Younger age, larger tumor size needing radiosurgery, and more extensive removal of tumor were associated with better tumor control.ConclusionMore extensive internal acoustic meatus tumor removal was associated with poor postoperative facial function and better tumor control.