The Journal of the International Society of Physical and Rehabilitation Medicine (Jan 2022)

A randomized controlled trial to compare the effect of ultrasound-guided, single-dose platelet-rich plasma and corticosteroid injection in patients with carpal tunnel syndrome

  • Reni Benny,
  • Srikumar Venkataraman,
  • Asem Rangita Chanu,
  • U Singh,
  • Devasenathipathy Kandasamy,
  • Raghavendra Lingaiah

DOI
https://doi.org/10.4103/jisprm.JISPRM-000164
Journal volume & issue
Vol. 5, no. 3
pp. 90 – 96

Abstract

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Background: Platelet-rich plasma (PRP) may aid functional recovery in compressive neuropathies. Objective: To compare the effect of autologous PRP with corticosteroid injection in patients with refractory carpal tunnel syndrome (CTS). Materials and Methods: This was a randomized controlled trial on 84 adults, who received either single-dose, ultrasound-guided PRP or corticosteroid. Boston Carpal Tunnel Questionnaire and cross-sectional area of median nerve were assessed at 0, 4, and 12 weeks. Results: A statistically significant 54.76% improvement (P < 0.05) in functional status was observed in both the groups at 12 weeks. Conclusion: PRP is as effective as corticosteroids in relieving pain and improving function in CTS.

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