Nature Communications (Sep 2022)
In situ analysis of nanoparticle soft corona and dynamic evolution
- Didar Baimanov,
- Jing Wang,
- Jun Zhang,
- Ke Liu,
- Yalin Cong,
- Xiaomeng Shi,
- Xiaohui Zhang,
- Yufeng Li,
- Xiumin Li,
- Rongrong Qiao,
- Yuliang Zhao,
- Yunlong Zhou,
- Liming Wang,
- Chunying Chen
Affiliations
- Didar Baimanov
- CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, Institute of High Energy Physics & National Center for Nanoscience and Technology of China, Chinese Academy of Sciences
- Jing Wang
- State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University
- Jun Zhang
- Zhejiang Engineering Research Center for Tissue Repair Materials, Wenzhou Institute, University of Chinese Academy of Sciences
- Ke Liu
- CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, Institute of High Energy Physics & National Center for Nanoscience and Technology of China, Chinese Academy of Sciences
- Yalin Cong
- CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, Institute of High Energy Physics & National Center for Nanoscience and Technology of China, Chinese Academy of Sciences
- Xiaomeng Shi
- State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University
- Xiaohui Zhang
- State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University
- Yufeng Li
- CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, Institute of High Energy Physics & National Center for Nanoscience and Technology of China, Chinese Academy of Sciences
- Xiumin Li
- CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, Institute of High Energy Physics & National Center for Nanoscience and Technology of China, Chinese Academy of Sciences
- Rongrong Qiao
- CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, Institute of High Energy Physics & National Center for Nanoscience and Technology of China, Chinese Academy of Sciences
- Yuliang Zhao
- CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, Institute of High Energy Physics & National Center for Nanoscience and Technology of China, Chinese Academy of Sciences
- Yunlong Zhou
- Zhejiang Engineering Research Center for Tissue Repair Materials, Wenzhou Institute, University of Chinese Academy of Sciences
- Liming Wang
- CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, Institute of High Energy Physics & National Center for Nanoscience and Technology of China, Chinese Academy of Sciences
- Chunying Chen
- CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, Institute of High Energy Physics & National Center for Nanoscience and Technology of China, Chinese Academy of Sciences
- DOI
- https://doi.org/10.1038/s41467-022-33044-y
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 14
Abstract
Characterizing the soft protein corona on nanoparticles i.e. the outer layer of the corona, remains a longstanding challenge. Here, the authors develop an in situ method to monitor the dynamic processes of multilayered corona formation and evolution that offers a universal strategy to characterize the soft corona proteome.
