Türk Osteoporoz Dergisi (Mar 2006)
The Relationship of Osteoporosis and Hyperlipidemia - Original Investigation
Abstract
Objective: The relation between osteoporosis (OP) and hyperlipidemia (HL) has not been fully clarified. We aimed to determine if there is a relation in between osteoporosis and hyperlipidemia. Material and Methods: Patients of whom bone mineral density (BMD) scores that have been defined by dual energy x-ray absorptiometry (DEXA) belonging to femoral and lumbar region, have been included in the study. As a result of BMD measurement patients who had T score -1 was accepted as normal. Patients who have been under the treatment of OP and who had used lipid reducers were eliminated from the study. In addition to this, patients who have OP secondary to another reason were eliminated, too. Lipid (total cholesterol, HDL, LDL, triglyceride) levels were also recorded. Results: Average total cholesterol and LDL levels were respectively 216 mg/dl and 128 mg/dl in patients with OP, 194 mg/dl and 111 mg/dl in patients with osteopenia and 180 mg/dl and 100 mg/dl in normal people and statistically significant difference has been found regarding total cholesterol levels and LDL levels in between patients with OP and patients with normal BMD (respectively p=0.03 and p=0.01). Femoral region total T scores (FTT) of patients with hypercholesterolemia was -0.92 and lumbar region total T scores(LTT) of patients with hypercholesterolemia was -1.89. T scores of patients with normal cholesterol levels were respectively -0.26 and -0.92. As a result when FTT and LTT were compared, in patients with normal level of cholesterol and with hypercholesterolemia, statistically significant difference has been found (respectively p=0.01 and p=0.001). Conclusion: There is a significant relation in between total cholesterol and LDL levels, and osteoporosis development. It can be useful to do research about osteoporosis on patients with hyperlipidemia. (Osteoporoz Dünyasından 2006; 12 (1): 1-4)
