PLoS ONE (Jan 2019)

Reinforcement of patient education improved physicians' adherence to guideline-recommended medical therapy after acute coronary syndrome.

  • Chih-Kuo Lee,
  • Chao-Lun Lai,
  • Ming-Hsien Lee,
  • Fang-Ying Su,
  • Tzu-Shan Yeh,
  • Li-Ying Cheng,
  • Mu-Yang Hsieh,
  • Yen-Wen Wu,
  • Yen-Bin Liu,
  • Chih-Cheng Wu

DOI
https://doi.org/10.1371/journal.pone.0217444
Journal volume & issue
Vol. 14, no. 6
p. e0217444

Abstract

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BackgroundPrescription of guideline-recommended medicines after acute coronary syndrome (ACS) has been suboptimal. Tools for improving the use of medications have been developed, but they mainly targeted physicians.ObjectiveWe evaluated the effects of reinforcement of patient and family education on the usage of guideline-recommended secondary prevention medications.MethodsThis was a retrospective analysis of a prospectively collected registry of patients with ACS who were admitted to a regional teaching hospital in Taiwan between February 2015 and April 2017. The control group included 76 patients discharged before implementing the electronic-based patient and family education (PFE) system. The intervention group included 206 patients discharged after implementation. The primary outcome was the prescription rate of all four guideline-recommended drugs. Predictors of adherence were also evaluated.ResultsThe study cohort included 282 ACS patients (188 men and 94 women) with a mean age of 68.5 years (standard deviation, 14.2). The intervention group patients were younger, had more family history of premature cardiovascular disease, more dyslipidemia, and underwent more reperfusion therapy. The intervention group was prescribed more guideline-recommended drugs than the control group: dual antiplatelet agents, 79.61% vs. 47.37% (pConclusionsReinforcement of patient education was associated with significant improvements in physicians' adherence to guideline-recommended medical therapy after acute coronary syndrome.