Concurrent Deep Vein Thrombosis and Pulmonary Embolism Associated with Hyperthyroidism: a Case Report

Abstract

Numerous disorders of coagulation and fibrinolysis have been reported in patients with thyroid diseases, especially with hyperthyroidism. Most articles are focused on deep vein thrombosis risk, however, few of them describe association between hyperthyroidism and pulmonary embolism. We report a case of a 43-year-old woman with long-term uncontrolled hyperthyroidism complicated by venous thromboembolism. The potential mechanisms could be endothelial dysfunction, decreased fibrinolytic activity, and increased levels of coagulation factors. Thyroid evaluation should be recommended in patients with unprovoked venous thromboembolic events.

Keywords

• Hyperthyroidism
• Pulmonary embolism
• Venous thromboembolism
• Deep vein thrombosis