Nature Communications (Feb 2023)
Optimal age targeting for pneumococcal vaccination in older adults; a modelling study
- Deus Thindwa,
- Samuel Clifford,
- Jackie Kleynhans,
- Anne von Gottberg,
- Sibongile Walaza,
- Susan Meiring,
- Todd D. Swarthout,
- Elizabeth Miller,
- Peter McIntyre,
- Nick Andrews,
- Zahin Amin-Chowdhury,
- Norman Fry,
- Kondwani C. Jambo,
- Neil French,
- Samanta Cristine Grassi Almeida,
- Shamez N. Ladhani,
- Robert S. Heyderman,
- Cheryl Cohen,
- Maria Cristina de Cunto Brandileone,
- Stefan Flasche
Affiliations
- Deus Thindwa
- Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine
- Samuel Clifford
- Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine
- Jackie Kleynhans
- Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service
- Anne von Gottberg
- Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service
- Sibongile Walaza
- Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service
- Susan Meiring
- Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service
- Todd D. Swarthout
- Malawi Liverpool Wellcome Research Programme
- Elizabeth Miller
- Department of Infectious Disease Epidemiology London School of Hygiene & Tropical Medicine
- Peter McIntyre
- University of Otago
- Nick Andrews
- Immunisation and Countermeasures Division, UK Health Security Agency
- Zahin Amin-Chowdhury
- Immunisation and Countermeasures Division, UK Health Security Agency
- Norman Fry
- Immunisation and Countermeasures Division, UK Health Security Agency
- Kondwani C. Jambo
- Malawi Liverpool Wellcome Research Programme
- Neil French
- Malawi Liverpool Wellcome Research Programme
- Samanta Cristine Grassi Almeida
- National Laboratory for Meningitis and Pneumococcal Infections, Laboratory for Meningitis, Pneumonia and Pneumococcal Infection, Centre of Bacteriology
- Shamez N. Ladhani
- Immunisation and Countermeasures Division, UK Health Security Agency
- Robert S. Heyderman
- Malawi Liverpool Wellcome Research Programme
- Cheryl Cohen
- Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service
- Maria Cristina de Cunto Brandileone
- National Laboratory for Meningitis and Pneumococcal Infections, Laboratory for Meningitis, Pneumonia and Pneumococcal Infection, Centre of Bacteriology
- Stefan Flasche
- Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine
- DOI
- https://doi.org/10.1038/s41467-023-36624-8
- Journal volume & issue
-
Vol. 14,
no. 1
pp. 1 – 8
Abstract
Vaccination against invasive pneumococcal disease is recommended for older adults but the optimal age group to target has not been determined and may vary by epidemiological setting. Here, the authors use statistical modelling to estimate the optimal ages for vaccination in Brazil, England, Malawi, and South Africa.
