Premalignant gastric lesions in patients included in National colorectal cancer screening

Abstract

Gastric cancer is the fifth most common malignancy in the world with almost one million new cases annually. Helicobacter pylori infection causes 89% of all gastric cancers. Premalignant lesions (atrophy and intestinal metaplasia) develop after several decades of inflammation. Secondary prevention with gastroscopy is possible, but it is costly and has a low compliance rate. Alternative procedures like serology testing for pepsinogen I and II and pepsinogen I/II ratio are available to select patients for surveillance gastroscopies.

Keywords

• gastropanel
• helicobacer pylori
• atrophy
• intestinal metaplasia
• gastric cancer