Fecal Microbiota Transplantation for Severe Infant Botulism, China

Abstract

Infant botulism in a 4-month-old boy in China who continued to excrete toxins for over a month despite antitoxin therapy was further treated with fecal microbiota transplantation. After treatment, we noted increased gut microbial diversity and altered fecal metabolites, which may help reduce intestinal pH and enhance anti-inflammatory capabilities.

Keywords

• Infant botulism
• Clostridium botulinum
• fecal microbiota transplantation
• source-tracking
• gut microbiome
• targeted metabolomics