Deletion of GPR21 improves glucose homeostasis and inhibits the CCL2-CCR2 axis by divergent mechanisms

• Jean-Francois Gautier,
• Nicolas Venteclef,
• Assam El-Osta,
• Andrew J Murphy,
• Darren M Riddy,
• Helene L Kammoun,
• Sanja Bosnyak-Gladovic,
• Rocio De la Fuente Gonzalez,
• Jon Merlin,
• Mark Ziemann,
• Stewart Fabb,
• Tracie L Pierce,
• Natalie Diepenhorst,
• Patricia Rueda,
• William N Charman,
• Arthur Christopoulos,
• Patrick M Sexton,
• Roger J Summers,
• Mark A Febbraio,
• Philippe Delerive,
• Christopher J Langmead

Affiliations

Jean-Francois Gautier

Inserm UMRS 1138, Département Diabète et Endocrinologie, Sorbonne Université, Paris, France

Nicolas Venteclef

Inserm UMRS 1138, Département Diabète et Endocrinologie, Sorbonne Université, Paris, France

Assam El-Osta

Department of Diabetes, Monash University Central Clinical School, Melbourne, Victoria, Australia

Andrew J Murphy

Haematopoiesis and Leukocyte Biology, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia

Darren M Riddy

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, Victoria, Australia

Helene L Kammoun

Haematopoiesis and Leukocyte Biology, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia

Sanja Bosnyak-Gladovic

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, Victoria, Australia

Rocio De la Fuente Gonzalez

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, Victoria, Australia

Jon Merlin

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, Victoria, Australia

Mark Ziemann

Department of Diabetes, Monash University Central Clinical School, Melbourne, Victoria, Australia

Stewart Fabb

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, Victoria, Australia

Tracie L Pierce

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, Victoria, Australia

Natalie Diepenhorst

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, Victoria, Australia

Patricia Rueda

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, Victoria, Australia

William N Charman

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, Victoria, Australia

Arthur Christopoulos

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, Victoria, Australia

Patrick M Sexton

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, Victoria, Australia

Roger J Summers

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, Victoria, Australia

Mark A Febbraio

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, Victoria, Australia

Philippe Delerive

Pôle d`Innovation Thérapeutique Métabolisme, Institut de Recherches Internationales Servier, Suresnes, France

Christopher J Langmead

Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, Victoria, Australia