Wellcome Open Research (Jul 2018)
Know Your Heart: Rationale, design and conduct of a cross-sectional study of cardiovascular structure, function and risk factors in 4500 men and women aged 35-69 years from two Russian cities, 2015-18 [version 2; referees: 3 approved]
- Sarah Cook,
- Sofia Malyutina,
- Alexander V Kudryavtsev,
- Maria Averina,
- Natalia Bobrova,
- Sergey Boytsov,
- Soren Brage,
- Taane G. Clark,
- Ernest Diez Benavente,
- Anne Elise Eggen,
- Laila A Hopstock,
- Alun Hughes,
- Heidi Johansen,
- Kamila Kholmatova,
- Anastasiya Kichigina,
- Anna Kontsevaya,
- Michael Kornev,
- Darryl Leong,
- Per Magnus,
- Ellisiv Mathiesen,
- Martin McKee,
- Katy Morgan,
- Odd Nilssen,
- Ilya Plakhov,
- Jennifer K Quint,
- Alicja Rapala,
- Andrey Ryabikov,
- Lyudmila Saburova,
- Henrik Schirmer,
- Marina Shapkina,
- Suhail Shiekh,
- Vladimir M Shkolnikov,
- Michael Stylidis,
- Michael Voevoda,
- Kate Westgate,
- David A Leon
Affiliations
- Sarah Cook
- London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK
- Sofia Malyutina
- Research Institute of Internal and Preventive Medicine, Branch of Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090, Russian Federation
- Alexander V Kudryavtsev
- Northern State Medical University, Arkhangelsk, 163000, Russian Federation
- Maria Averina
- UiT the Arctic University of Norway, Tromsø, 9037, Norway
- Natalia Bobrova
- London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK
- Sergey Boytsov
- Federal State budget organization, National medical research center of cardiology, Russian Ministry of Health, Moscow, 121552, Russian Federation
- Soren Brage
- MRC Epidemiology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, CB2 0QQ, UK
- Taane G. Clark
- London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK
- Ernest Diez Benavente
- London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK
- Anne Elise Eggen
- UiT the Arctic University of Norway, Tromsø, 9037, Norway
- Laila A Hopstock
- UiT the Arctic University of Norway, Tromsø, 9037, Norway
- Alun Hughes
- UCL Institute of Cardiovascular Science, University College London, London, WC1E 6BT, UK
- Heidi Johansen
- UiT the Arctic University of Norway, Tromsø, 9037, Norway
- Kamila Kholmatova
- Northern State Medical University, Arkhangelsk, 163000, Russian Federation
- Anastasiya Kichigina
- London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK
- Anna Kontsevaya
- National research center for preventive medicine, Moscow, 101990, Russian Federation
- Michael Kornev
- Northern State Medical University, Arkhangelsk, 163000, Russian Federation
- Darryl Leong
- McMaster University , Ontario, L8S 4K1, Canada
- Per Magnus
- Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, 0851, Norway
- Ellisiv Mathiesen
- UiT the Arctic University of Norway, Tromsø, 9037, Norway
- Martin McKee
- London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK
- Katy Morgan
- London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK
- Odd Nilssen
- UiT the Arctic University of Norway, Tromsø, 9037, Norway
- Ilya Plakhov
- Lytech Laboratory LLC, Moscow, 107023, Russian Federation
- Jennifer K Quint
- Royal Brompton Campus, Imperial College London, London, SW3 6LY, UK
- Alicja Rapala
- UCL Institute of Cardiovascular Science, University College London, London, WC1E 6BT, UK
- Andrey Ryabikov
- Research Institute of Internal and Preventive Medicine, Branch of Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090, Russian Federation
- Lyudmila Saburova
- Institute of Philosophy and Law, Ural Branch of the Russian Academy of Sciences, Ekaterinburg, 620990, Russian Federation
- Henrik Schirmer
- Akerhus University Hospital, Oslo, 1478, Norway
- Marina Shapkina
- Research Institute of Internal and Preventive Medicine, Branch of Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090, Russian Federation
- Suhail Shiekh
- London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK
- Vladimir M Shkolnikov
- Max Planck Institute for Demographic Research, Rostock, 18057, Germany
- Michael Stylidis
- UiT the Arctic University of Norway, Tromsø, 9037, Norway
- Michael Voevoda
- Research Institute of Internal and Preventive Medicine, Branch of Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630090, Russian Federation
- Kate Westgate
- MRC Epidemiology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, CB2 0QQ, UK
- David A Leon
- London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK
- DOI
- https://doi.org/10.12688/wellcomeopenres.14619.2
- Journal volume & issue
-
Vol. 3
Abstract
Russia has one of the highest rates of cardiovascular disease in the world. The International Project on Cardiovascular Disease in Russia (IPCDR) was set up to understand the reasons for this. A substantial component of this study was the Know Your Heart Study devoted to characterising the nature and causes of cardiovascular disease in Russia by conducting large cross-sectional surveys in two Russian cities Novosibirsk and Arkhangelsk. The study population was 4542 men and women aged 35-69 years recruited from the general population. Fieldwork took place between 2015-18. There were two study components: 1) a baseline interview to collect information on socio-demographic characteristics and cardiovascular risk factors, usually conducted at home, and 2) a comprehensive health check at a primary care clinic which included detailed examination of the cardiovascular system. In this paper we describe in detail the rationale for, design and conduct of these studies.
