Menopause Review (Feb 2011)
Zaburzenia funkcji poznawczych po menopauzie – problem ciągle aktualny
Abstract
One third of a woman’s life is around or after the menopause. Nowadays a 50-year old woman is a full-timeworking person expected to be fully active in intellectual, physical and social terms. The study focuses on the areaof cognitive dysfunction among women after the menopause. It determines their participation in professional,family and social life.The study is a review of literature on the role hormonal changes play in originating cognitive dysfunctionafter the menopause and potential modification of neuropsychogenic function by estrogens depending on theselected gene polymorphisms. It hypothesises that estrogen deficiency and variations in LH level may initiatecognitive dysfunction. The authors are inclined to consider this because of the not fully understood processesof hormonal axis dysfunction in connection with progressive disorder of cognitive function over time. Thisresults in lack of uniform standards of preventive measures and treatment of such health problems in thisgroup of patients.Assessment of cognitive dysfunction in this group of patients and their correlation with a type of hormonaldysfunction, gene polymorphism or environmental conditions such as health behavior and diet, would facilitate dostaractionsleading to adequate prophylaxis, improvement quality of life as well as proposing new forms andmethods of therapy. In the longer term this would be positive in health, economic and social terms.
